IS NEMBUTAL A BARBITURATE FUNDAMENTALS EXPLAINED

Contraindicated (1)pentobarbital will reduce the extent or influence of roflumilast by impacting hepatic/intestinal enzyme CYP3A4 metabolism.Barbiturates can induce hepatic microsomal enzymes resulting in amplified metabolism and reduced anticoagulant response of oral anticoagulants (eg, warfarin, acenocoumarol, dicumarol, and phenprocoumon); suffe